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Humanized immunoglobulins and methods of making the same
Inventors: Cary L. Queen; Harold E. Selick 2. 9 5595756
Liposomal compositions for enhanced retention of bioactive agents
Inventors: Marcel Bally; Nancy Boman; Pieter R. Cullis; Lawrence Mayer 3. 8 7745391
Human thrombospondin polypeptide
Inventors: Liat Mintz; Hanqing Xie; Dvir Dahary; Erez Levanon; Shiri Freilich; Nili Beck; Wei-Yong Zhu; Alon Wasserman; Jeanne Bernstein 4. 7 6737056
Polypeptide variants with altered effector function
Inventors: Leonard G. Presta 4. 7 8697359
CRISPR-Cas systems and methods for altering expression of gene products
Inventors: Feng Zhang 4. 7 9637739
RNA-directed DNA cleavage by the Cas9-crRNA complex
Inventors: Virginijus {hacek over (S)}ik{hacek over (s)}nys; Giedrius Gasiunas; Tautvydas Karvelis 7. 6 10584352
Methods for engineering T cells for immunotherapy by using RNA-guided Cas nuclease system
Inventors: Philippe Duchateau; Andre Choulika; Laurent POIROT 7. 6 5288931
Method for refolding insoluble, misfolded insulin-like growth factor-I into an active conformation
Inventors: Judy Y. Chang; Nancy C. McFarland; James R. Swartz 7. 6 7112660
Modified cytokine
Inventors: Helena Domingues; Hartmut Oschkinat; Luis Serrano; Joerg Peters 7. 6 7691997
Functional and hyperfunctional siRNA
Inventors: Anastasia Khvorova; Angela Reynolds; Devin Leake; William Marshall; Stephen Scaringe; Steven Read 7. 6 9061059
Modified polynucleotides for treating protein deficiency
Inventors: Tirtha Chakraborty; Antonin de Fougerolles; Ron Weiss |